LISC's local partners include:

• Baton Rouge Area Foundation
• Centro Campesino Farmworker Center, Inc.
• Enterprise Corporation of the Delta
• Everglades Community Association
• Foundation for the Mid South
• Mercy Housing and Human Development
• New Orleans Neighborhood Development Collaborative
• Pearl River Valley Opportunity, Inc
• Pineywoods Home Team
• Southern Mutual Help Association, Inc.

LISC's national programs are also working in partnership with city and state governments to develop appropriate strategies and tools to rebuild devastated neighborhoods and rural areas.

• LISC's Housing Authority Resource Center (HARC) and NEF together are helping housing authorities in Mississippi and Louisiana apply for housing credits – an important step to create additional affordable rental housing.
• LISC's Community Investment Collaborative for Kids (CICK) has a contract with Louisiana's Department of Social Services to target $7.5 million in federal funds to rebuild child care centers.
• LISC's Vacant Properties Initiative is advising the City of New Orleans and community groups there on strategies to develop both land banks and property and land acquisition practices.